Systems and methods are provided for interacting with an Application Programming Interface (API) using a digital signature. In one embodiment, a system includes one or more processors that execute the instructions to perform operations. The operations may include receiving a first digital signature from a requesting device, the first digital signature being associated with a first set of fields in the database; identifying one or more requested fields; accessing the database to retrieve the information associated with the one or more requested fields, the information being associated with at least one API; and providing a response to the requesting device to cause a requesting application to consume the response from the API.