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US Patent 11654193 Cancer treatment combinations

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 US Patent 11654193 Cancer treatment combinations

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There are provided, inter alia, compositions and methods for treatment of cancer. The methods include administering to a subject in need a therapeutically effective amount of a Bruton's tyrosine kinase (BTK) antagonist and a ROR-1 antagonist. Further provided are pharmaceutical compositions including a BTK antagonist, ROR-1 antagonist and a pharmaceutically acceptable excipient. In embodiments, the BTK antagonist is ibrutinib and the ROR-1 antagonist is cirmtuzumab.

Infobox
Is a
Patent
Patent
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
116541930
Date of Patent
May 23, 2023
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Patent Application Number
168708030
Date Filed
May 8, 2020
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Patent Primary Examiner
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Karen A. Canella
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CPC Code
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A61K 2300/00
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A61K 45/06
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A61K 2039/505
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