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US Patent 11638699 Intestinal alkaline phosphatase formulations

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Steven Hubert0

James Gubbins0

Michael Kaleko0

Ray Stapleton0

Andrew Bristol0

Christian Furlan Freguia0

Cristina Freire0

Date of Patent

May 2, 2023

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Patent Application Number

169822360

Date Filed

March 20, 2019

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Patent Citations

US Patent 10449236 Treating seizure with recombinant alkaline phosphatase

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US Patent 10603361 Methods of treating a subject with an alkaline phosphatase deficiency

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US Patent 10570380 Downstream processing of an alkaline phosphatase

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US Patent 10987410 Alkaline phosphatase formulations

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US Patent 10000532 Bone delivery conjugates and method of using same to target proteins to bone

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US Patent 10052366 Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof

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Patent Primary Examiner

Hope A Robinson

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The present invention provides for a formulation comprising an active alkaline phosphatase (AP)-based agent and an enteric agent, wherein the formulation is suitable for releasing a substantial amount of the active AP-based agent in the intestines.

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