US Patent 11617357 Humanized light chain mice
Patent 11617357 was granted and assigned to Regeneron Pharmaceuticals on April, 2023 by the United States Patent and Trademark Office.
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Patent Inventor Names
Andrew J. Murphy0
Cagan Gurer0
Karolina A. Hosiawa0
Lynn Macdonald0
Sean Stevens0
Edits on 25 Apr, 2023
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US Patent 11617357 Humanized light chain mice
Article
Non-human animals, tissues, cells, and genetic material are provided that comprise a modification of an endogenous non-human heavy chain immunoglobulin sequence and that comprise an ADAM6 activity functional in a mouse, wherein the non-human animals express a human immunoglobulin heavy chain variable domain and a cognate human immunoglobulin λ light chain variable domain.
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Is a
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
116173570
Date of Patent
April 4, 2023
0Patent Application Number
167297980
Date Filed
December 30, 2019
0Patent Citations
Patent Primary Examiner
CPC Code
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