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US Patent 11617357 Humanized light chain mice

Patent 11617357 was granted and assigned to Regeneron Pharmaceuticals on April, 2023 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
Regeneron Pharmaceuticals
Regeneron Pharmaceuticals
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Current Assignee
Regeneron Pharmaceuticals
Regeneron Pharmaceuticals
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
116173570
Patent Inventor Names
Sean Stevens0
Andrew J. Murphy0
Cagan Gurer0
Karolina A. Hosiawa0
Lynn Macdonald0
Date of Patent
April 4, 2023
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Patent Application Number
167297980
Date Filed
December 30, 2019
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Patent Citations
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US Patent 10577430 ADAM6 mice
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US Patent 10072095 ADAM6 mice
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US Patent 10266803 Human lambda light chain mice
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US Patent 10694725 ADAM6 mice
Patent Primary Examiner
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Ram R. Shukla
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CPC Code
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A01K 67/0278
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Non-human animals, tissues, cells, and genetic material are provided that comprise a modification of an endogenous non-human heavy chain immunoglobulin sequence and that comprise an ADAM6 activity functional in a mouse, wherein the non-human animals express a human immunoglobulin heavy chain variable domain and a cognate human immunoglobulin λ light chain variable domain.

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