A system for closed loop prefix management for white boxes includes a network device, a route reflector coupled to the network device, a software defined network controller coupled to the route reflector and the network device, and a prefix usage analyzer in the software defined network controller. The prefix usage analyzer determines usage attributes of prefixes and identifies the prefixes with a predetermined usage attribute. The software defined network controller instructs a network controller in the network device to store the prefixes with the predetermined usage attributes in a table in the network device.