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US Patent 11576910 Methods of treating heart failure with cardiac sarcomere activators

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Is a
Patent
Patent

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11576910
Date of Patent
February 14, 2023
Patent Application Number
16625958
Date Filed
June 29, 2018
Patent Citations
‌
US Patent 10543215 Combination therapy of cardiac myosin activator and sinus node if current inhibitor
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US Patent 10421726 Heterocyclic compounds and their uses
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US Patent 10975034 Compounds, compositions and methods
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US Patent 10035770 Compounds, compositions and methods
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US Patent 10385023 Compounds, compositions and methods
Patent Citations Received
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US Patent 11986474 Methods for treating heart failure by administering cardiac sarcomere activators
0
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US Patent 11753394 Synthesis of omecamtiv mecarbil
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US Patent 11884630 Heterocyclic compounds and their uses
0
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US Patent 11926592 Salts and crystal forms of omecamtiv mecarbil
0
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US Patent 11931358 Methods of treating heart failure with cardiac sarcomere activators
0
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US Patent 11958809 Salt of omecamtiv mecarbil and process for preparing salt
0
Patent Primary Examiner
‌
Kortney L. Klinkel
CPC Code
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A61K 31/496
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A61K 9/0053
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A61P 9/04

Provided herein are methods of treating a subject with heart failure, comprising administering to the subject an initial dose of a cardiac sarcomere activator (CSA) for an initial time period, and subsequently administering to the subject a dose of the CSA based on the subject's plasma concentration of the CSA at the end of the initial time period.

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