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US Patent 11535882 Methods and compositions for combinatorial barcoding

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Contents

Is a
Patent
Patent

Patent attributes

Patent Applicant
Cellular Research
Cellular Research
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11535882
Date of Patent
December 27, 2022
Patent Application Number
15084307
Date Filed
March 29, 2016
Patent Citations
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US Patent 10030267 Methods and systems for processing polynucleotides
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US Patent 10041116 Methods and systems for processing polynucleotides
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US Patent 10131958 Massively parallel single cell analysis
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US Patent 10002316 Spatially addressable molecular barcoding
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US Patent 10011872 Methods and systems for processing polynucleotides
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US Patent 10017761 Methods for preparing cDNA from low quantities of cells
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US Patent 10023910 Multiple tagging of individual long DNA fragments
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US Patent 10208343 Methods and systems for processing polynucleotides
...
Patent Citations Received
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US Patent 11993814 Digital counting of individual molecules by stochastic attachment of diverse labels
0
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US Patent 12060607 Digital counting of individual molecules by stochastic attachment of diverse labels
0
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US Patent 12071617 Hybrid targeted and whole transcriptome amplification
0
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US Patent 12084712 Sample indexing for single cells
0
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US Patent 11649497 Methods and compositions for quantitation of proteins and RNA
0
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US Patent 11702706 Massively parallel single cell analysis
0
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US Patent 11773436 Using random priming to obtain full-length V(D)J information for immune repertoire sequencing
‌
US Patent 11782059 Measurement of protein expression using reagents with barcoded oligonucleotide sequences
...
Patent Primary Examiner
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Robert H Havlin
CPC Code
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C12Q 1/6806
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C12Q 2563/185
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C12Q 1/6837
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C12Q 1/6869

The present disclosure provide compositions, methods and kits for generating a set of combinatorial barcodes, and uses thereof for barcoding samples such as single cells or genomic DNA fragments. Some embodiments disclosed herein provide compositions comprising a set of component barcodes for producing a set of combinatorial barcodes. The set of component barcodes can comprise, for example, n×m unique component barcodes, wherein n and m are integers, each of the component barcodes comprises: one of n unique barcode subunit sequences; and one or two linker sequences or the complements thereof, wherein the component barcodes are configured to connect to each other through the one or two linker sequences or the complements thereof to produce a set of combinatorial barcodes.

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