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US Patent 11535681 Sickled beta globin antibodies

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Patent
Patent

Patent attributes

Patent Applicant
Bluebird Bio
Bluebird Bio
Current Assignee
Bluebird Bio
Bluebird Bio
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11535681
Date of Patent
December 27, 2022
Patent Application Number
16771411
Date Filed
December 14, 2018
Patent Primary Examiner
‌
Michael Szperka

The invention generally provides improved anti-sickled-globin antibodies and fragments thereof. In particular embodiments, the antibody or antigen binding fragment thereof recognizes the βs, Glu6Val mutation. In various embodiments, the invention provides a conjugate comprising an anti-βs-globin antibody or antigen binding fragment thereof and a detectable label. In particular embodiments, a hybridoma comprising an anti-βs-globin antibody contemplated herein is provided.

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