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US Patent 11479776 Expression system

Patent 11479776 was granted and assigned to Fujifilm Diosynth Biotechnologies UK Limited on October, 2022 by the United States Patent and Trademark Office.

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Patent Applicant
Fujifilm Diosynth Biotechnologies UK Limited
Fujifilm Diosynth Biotechnologies UK Limited
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Current Assignee
Fujifilm Diosynth Biotechnologies UK Limited
Fujifilm Diosynth Biotechnologies UK Limited
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
114797760
Patent Inventor Names
Christopher Lennon0
Date of Patent
October 25, 2022
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Patent Application Number
164971020
Date Filed
March 14, 2018
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Patent Primary Examiner
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Suzanne M Noakes
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A protein expression system for use in a prokaryotic host is provided, the expression system comprising: a) an expression cassette comprising a nucleic acid sequence encoding a protein of interest operably linked to a T7 RNA polymerase-dependent promoter; and b) an expression cassette comprising a nucleic acid sequence encoding T7 RNA polymerase operably linked to a host polymerase-dependent λ phage promoter and a single perfect palindrome operator sequence; wherein the expression cassette for T7 RNA polymerase is located on the chromosome of a host cell.

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