Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Nishith Chaturvedi0
Pradeep Dinesh Shahi0
Rajamannar Thennati0
Ravishankara Madavati Nagaraja0
Rishit Mansukhlal Zalawadia0
Vinod Sampatrao Burade0
Vipulkumar Shankarbhai Patel0
Abhishek Tiwari0
...
Date of Patent
September 20, 2022
0Patent Application Number
163761900
Date Filed
April 5, 2019
0Patent Primary Examiner
The present disclosure pertains to novel Glucagon like Peptide-1 (GLP-1) (7-37) analogs having an amino acid sequence with Leu or Ile at the C-terminal. The new analogs are potent GLP-1 agonists with reduced adverse effect and improved duration of action. The present disclosure further relates to acylated derivatives of the new analogs which have further improved potency and duration of action and are suitable for oral administration. The analogs of present disclosure may be useful in treatment of diabetes and obesity.
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