Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Minyong Chen0
Aihua Zhang0
Ming-Qun Xu0
James C. Samuelson0
Pingfang Liu0
Margaret Heider0
Date of Patent
July 19, 2022
0Patent Application Number
171291120
Date Filed
December 21, 2020
0Patent Primary Examiner
CPC Code
Provided herein is a thermolabile proteinase and methods of using the same. In some embodiments, the thermolabile proteinase may comprise an amino acid sequence that is at least 90% identical to any of SEQ ID NOs:1-11 and at least one amino acid substitution in helix 3. The thermolabile proteinase is active at a temperature in the range of 4° C.-40° C. and is inactivated by raising the temperature to above 50° C., where the proteinase is substantially inactive at 65° C.
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