Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Juhan Kim0
Aamir Mir0
Benjamin Mijts0
Date of Patent
May 17, 2022
0Patent Application Number
175678000
Date Filed
January 3, 2022
0Patent Citations
...
Patent Primary Examiner
CPC Code
The present disclosure provides new RNA-guided nucleases for making rational, direct edits to nucleic acids in live cells; specifically, the present disclosure provides Type V MAD nucleases (e.g., RNA-guided nucleases or RGNs) with altered PAM preferences and/or altered activity at different temperatures or fidelity, and/or varied nuclease activities; all changes that may increase the versatility of a nucleic acid-guided nuclease for certain editing tasks.
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