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US Patent 11312763 Anti-N3pGlu amyloid beta peptide antibodies and uses thereof

Patent 11312763 was granted and assigned to Eli Lilly and Company on April, 2022 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
0

Patent attributes

Patent Applicant
Eli Lilly
Eli Lilly
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Current Assignee
Eli Lilly
Eli Lilly
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
113127630
Patent Inventor Names
Ronald Bradley Demattos0
Michael Carl Irizarry0
Date of Patent
April 26, 2022
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Patent Application Number
163106290
Date Filed
June 23, 2017
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Patent Primary Examiner
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Kimberly Ballard
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CPC Code
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C07K 2317/92
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C07K 2317/56
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C07K 2317/565
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A61P 25/28
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A61K 2039/545
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A61K 39/3955
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C07K 2317/24
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C07K 16/18
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The invention is directed to a short term induction treatment with anti-N3pGlu Aβ antibodies of a disease characterized by deposition of Aβ in the brain, that include Alzheimer's disease (AD), Down's syndrome, and cerebral amyloid angiopathy (CAA). In certain embodiments, patients are administered an induction dose of 10 to 60 mg/kg of an anti-N3pGlu Aβ antibody for a period of 6 months or less.

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