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US Patent 11274103 Compounds for the modulation of MYC activity

Patent 11274103 was granted and assigned to Syros Pharmaceuticals on March, 2022 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Patent Applicant
Syros Pharmaceuticals
Syros Pharmaceuticals
Current Assignee
Syros Pharmaceuticals
Syros Pharmaceuticals
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11274103
Date of Patent
March 15, 2022
Patent Application Number
15699176
Date Filed
September 8, 2017
Patent Primary Examiner
‌
David K O'Dell
CPC Code
‌
C07D 495/04
Patent abstract

The present invention provides novel compounds of Formula (I) and pharmaceutically acceptable salts, solvates, hydrates, tautomers, stereoisomers, isotopically labeled derivatives, and compositions thereof. Also provided are methods and kits involving the compounds or compositions for treating or preventing proliferative diseases, e.g., cancers (e.g., breast cancer, prostate cancer, lymphoma, lung cancer, pancreatic cancer, ovarian cancer, neuroblastoma, or colorectal cancer), benign neoplasms, angiogenesis, inflammatory diseases, fibrosis (e.g., polycystic kidney disease), autoinflammatory diseases, and autoimmune diseases in a subject.

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