Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Stephanos Ioannidis0
Steven Mischke0
Alexandre Joseph Buckmelter0
Bingsong Han0
Cuixian Liu0
David James Richard0
Justin Caravella0
Matthew W. Martin0
...
Date of Patent
February 15, 2022
Patent Application Number
16753439
Date Filed
October 5, 2018
Patent Citations
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present disclosure relates to chemical entities useful as inhibitors of Ubiquitin Specific Protease 30 (USP30), pharmaceutical compositions comprising the chemical entities, and methods of using the chemical entities. The chemical entities as disclosed herein can be useful in the treatment of a disease, disorder, or condition involving mitochondrial dysfunction, including neurodegenerative diseases, motor neuron diseases, metabolic disorders, and cancers, among other ailments. Chemical entities disclosed herein include compounds of Formula (II):
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