US Patent 11229613 Compositions including epinephrine microcrystals
Patent 11229613 was granted and assigned to Nova Southeastern University on January, 2022 by the United States Patent and Trademark Office.
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The invention provides compositions including epinephrine fine particles, including epinephrine nanoparticles or nanocrystals and epinephrine microparticles or microcrystals, and methods for therapeutic use of the compositions for the treatment of conditions responsive to epinephrine such as a cardiac event or an allergic reaction, particularly anaphylaxis. The epinephrine fine particles can be incorporated into orally-disintegrating and fast-disintegrating tablet pharmaceutical formulations and can significantly increase the sublingual bioavailability of epinephrine, and thereby reduce the epinephrine dose required.
US Patent 11229613 Compositions including epinephrine microcrystals
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