Patent 11191849 was granted and assigned to Arbutus Biopharma Corporation on December, 2021 by the United States Patent and Trademark Office.
The present invention provides compositions comprising nucleic acid molecules, such as mRNA molecules, encapsulated within lipid particles. The compositions are useful, for example, to introduce the mRNA molecules into a human subject where they are translated to produce a polypeptide that functions to ameliorate one or more symptoms of a disease.