Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Tatyana Naryshkina0
Date of Patent
November 23, 2021
0Patent Application Number
161929930
Date Filed
November 16, 2018
0Patent Primary Examiner
Patent abstract
Disclosed are methods of determining activity of CDK4 and CDK6 variants upon exposure to CDK inhibitors, methods for determining activity of a Rb variant, methods for determining the activity of a p16 variant in a cell, and methods for determining the sensitivity of a CDK4 variant or a CDK6 variant to p16 in a cell. Stable cell lines for determining activity of CDK4 variants, CDK6 variants, Rb variants, and p16 variants are also disclosed.
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