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US Patent 11180481 Oxopiperazine helix mimetics as inhibitors of the p53-MDM2 interaction

Patent 11180481 was granted and assigned to New York University Press on November, 2021 by the United States Patent and Trademark Office.

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Patent abstract

The present invention relates to oligooxopiperazines for modulating the p53-Mdm2 interaction. Exemplary oligooxopiperazines include those of Formula IA, Formula IB, and Formula IC below (wherein the various substituents are as defined herein). Methods of using the oligooxopiperazines are also disclosed.

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