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US Patent 11118214 Hybridization compositions and methods

Patent 11118214 was granted and assigned to Agilent Technologies on September, 2021 by the United States Patent and Trademark Office.

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Current Assignee

Agilent Technologies

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Charles M. Hansen0

Kenneth H. Petersen0

Steen Hauge Matthiesen0

Tim Svenstrup Poulsen0

Date of Patent

September 14, 2021

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Patent Application Number

200905270

Date Filed

May 27, 2009

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Patent Citations Received

US Patent 11834703 Hybridization compositions and methods

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US Patent 11781185 Methods and reagents for nucleic acid analysis

US Patent 11287422 Multivalent binding composition for nucleic acid analysis

US Patent 12117438 Multivalent binding composition for nucleic acid analysis

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US Patent 12134766 Methods for generating circular nucleic acid molecules

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Patent abstract

The invention provides methods and compositions for hybridizing at least one molecule to a target. The invention may, for example, eliminate the use of or reduce the dependence on formamide in hybridization. Compositions for use in the invention include an aqueous composition comprising at least one nucleic acid sequence and at least one polar aprotic solvent in an amount effective to denature double-stranded nucleotide sequences.

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