Patent 11104658 was granted and assigned to ADT Pharmaceuticals, LLC on August, 2021 by the United States Patent and Trademark Office.
Disclosed are compounds, for example, a compound of formula I, wherein R, R0, R1-R8, n, X, Y, Y′, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition for example, cancer, mediated by the ras gene.