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US Patent 10995084 Pyrrolidine derivative

Patent 10995084 was granted and assigned to Kissei Pharmaceutical on May, 2021 by the United States Patent and Trademark Office.

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Patent Applicant
Kissei Pharmaceutical
Kissei Pharmaceutical
Current Assignee
Kissei Pharmaceutical
Kissei Pharmaceutical
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10995084
Date of Patent
May 4, 2021
Patent Application Number
16317934
Date Filed
July 20, 2017
Patent Primary Examiner
‌
Deepak R Rao
Patent abstract

The present invention aims to provide a novel compound which has CGRP receptor antagonist activity and which is useful for the treatment of various diseases mediated by CGRP receptors. That is, the present invention relates to the pyrrolidine derivatives represented by the following formula (I) or a pharmaceutically acceptable salt thereof. In the formulae, W is ring, X is a carbon atom or the like, Y1 to Y4 are carbon atoms or the like, and R1 to R7 is alkyl or the like. The compounds of the present invention or a pharmaceutically acceptable salt thereof have an excellent CGRP receptor antagonist activity, and thus are useful as agents for the treatment of various diseases mediated by CGRP receptors.

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