A tattoo machine control system comprises a holding arrangement (1) for storing tattoo needle cartridges (3) for the moment not attached to a tattoo machine and a tattoo machine controller configured to 5 control a tattoo machine based on a tattoo machine setting. The holding arrangement (1) has a plurality of slots, each slot (13) being arranged for receiving a respective tattoo needle cartridge (3). The system is configured to maintain an association of a tattoo machine setting for said tattoo machine with a slot (13) 10 of said plurality of slots. The tattooing process is made more efficient.