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US Patent 10980887 Sulfated alginate hydrogels for cell culture and therapy

Patent 10980887 was granted and assigned to ETH Zurich on April, 2021 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Patent Applicant
ETH Zurich
ETH Zurich
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Current Assignee
ETH Zurich
ETH Zurich
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
109808870
Patent Inventor Names
Stefanie Moller0
Marcy Zenobi-Wong0
Matthias Schnabelrauch0
Rami Mhanna0
Gemma Palazzolo0
Jana Becher0
Date of Patent
April 20, 2021
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Patent Application Number
159030700
Date Filed
February 23, 2018
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Patent Primary Examiner
‌
Taeyoon Kim
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Patent abstract

The present invention relates to a method for providing an embedded mammalian cell, comprising the steps of providing an alginate sulfate in aqueous solution; reacting the alginate sulfate to form a hydrogel in a gelation step, providing a precursor cell, and embedding the precursor cell in the sulfated alginate hydrogel in an embedding step, thus yielding an sulfated alginate hydrogel embedded cell. The invention further relates to sulfated alginate hydrogels, and cellular grafts comprising a mammalian cell embedded in sulfated alginate hydrogel.

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