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US Patent 10975126 MERS-CoV inhibitor peptides

Patent 10975126 was granted and assigned to King Faisal University on April, 2021 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Patent Applicant
King Faisal University
King Faisal University
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Current Assignee
King Faisal University
King Faisal University
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
109751260
Patent Inventor Names
Mohammed Al-Nazawi0
Abdulla Yousef Al-Taher0
Hyung-Joo Kwon0
Mahmoud Kandeel Elsayed0
Date of Patent
April 13, 2021
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Patent Application Number
168571360
Date Filed
April 23, 2020
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Patent Primary Examiner
‌
Ronald T Niebauer
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Patent abstract

The MERS-CoV inhibitor peptides include a set of peptides designed by modification or mutation of a wild type MERS-CoV fusion protein. The MERS-CoV inhibitor peptides are capable of inhibition of MERS-CoV membrane fusion, and thereby may prevent or slow the spread of MERS-CoV infections. Thus, the MERS-CoV inhibitor peptides may be used in pharmaceuticals to prevent and/or treat MERS-CoV infection. The pharmaceuticals may be formulated to comprise at least one of the MERS-CoV inhibitor peptides and a carrier, or they may include one or more expression systems capable of promoting cellular expression of one or more MERS-CoV inhibitor peptides. The MERS-CoV inhibitor peptides may also be used as reagents for MERS-CoV inhibition assays as a standard or reference inhibitors.

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