Implant inserters and related methods are disclosed herein, e.g., for delivering a fusion cage or other implant to a spinal disc space and for rotating or articulating the implant within the disc space. An exemplary instrument can include a slider that is slidably mounted to a body to define an implant clamp. A locking mechanism can allow the slider to be quickly disassembled from the body and for fast and convenient loading and unloading of an implant to the instrument. An actuation knob can be moved between a first position in which the implant is locked from rotating relative to the instrument and a second position in which the implant is retained to the instrument but allowed to rotate relative to the instrument.