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US Patent 10954496 Methods, systems, and reagents for direct RNA sequencing

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
Pacific Biosciences
Pacific Biosciences
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
109544960
Patent Inventor Names
Jeremiah Hanes0
Satwik Kamtekar0
Date of Patent
March 23, 2021
0
Patent Application Number
163548780
Date Filed
March 15, 2019
0
Patent Citations Received
‌
US Patent 12091657 Reverse transcriptase for nucleic acid sequencing
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Patent Primary Examiner
‌
Richard G Hutson
0
Patent abstract

Provided are compositions comprising recombinant polymerases that include amino acid substitutions, insertions, deletions, and/or exogenous features that confer modified properties upon the polymerase for sequencing RNA or RNA/DNA templates. Polymerases that topologically encircle the template nucleic acid are provided. Also provided are methods of using such polymerases to make a DNA or to sequence a template comprising RNA.

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