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US Patent 10947270 Targeted prodrug cytosine deaminase fusion carrier and application thereof

Patent 10947270 was granted and assigned to National Yang-Ming University on March, 2021 by the United States Patent and Trademark Office.

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Patent abstract

The present invention provides a targeted prodrug enzyme fusion carrier comprising a targeted molecule and a prodrug enzyme. The targeted prodrug enzyme fusion carrier can effectively identify and bind to tumor cells and tumor-induced tumor angiogenesis. The targeted prodrug enzyme fusion carrier also has a targeted prodrug enzyme fusion protein and a theranostic system utilizing the method of in vivo nuclear medicine for the clinical diagnosis and treatment of individual patients with tumors.

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