Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Yuelei Shen0
Xiaofei Zhou0
Yanan Guo0
Yang Bai0
Chaoshe Guo0
Rui Huang0
Date of Patent
March 16, 2021
0Patent Application Number
164289410
Date Filed
May 31, 2019
0Patent Primary Examiner
Patent abstract
This disclosure relates to genetically modified animal expressing human or chimeric (e.g., humanized) programmed death-ligand 1 (PD-L1, PDL1, or B7-H1), and methods of use thereof. In one aspect, the disclosure relates to genetically-modified, non-human animals whose genome comprises at least one chromosome comprising a sequence encoding a human or chimeric programmed death-ligand 1 (PD-L1).
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