Patent 10941395 was granted and assigned to Massachusetts Institute of Technology on March, 2021 by the United States Patent and Trademark Office.
The present disclosure relates to compositions and methods for modifying a gene sequence, and for systems for delivering such compositions. For example, the disclosure relates to modifying a gene sequence using a CRISPR-Cas9 or other nucleic acid editing system, and methods and delivery systems for achieving such gene modification, such as viral or non-viral delivery systems.