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US Patent 10913985 Predicting productivity in early cell line development

Patent 10913985 was granted and assigned to Lek (pharmaceutical company) on February, 2021 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Patent Applicant
Lek (pharmaceutical company)
Lek (pharmaceutical company)
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Current Assignee
Lek (pharmaceutical company)
Lek (pharmaceutical company)
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
109139850
Patent Inventor Names
Uro{hacek over (s)} Jamnikar0
Kristina Gruden0
Marjanca Blas0
Date of Patent
February 9, 2021
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Patent Application Number
155253240
Date Filed
November 12, 2015
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Patent Primary Examiner
‌
Channing S Mahatan
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Patent abstract

The present invention relates in general to the field of recombinant protein expression. In particular, the present invention relates to a method for selecting a suitable candidate cell clone for recombinant protein expression and to a host cell for recombinant protein expression, the host cell exhibiting artificially modified gene expression of at least one gene selected from the group consisting of: Fkbp10, ZdhhC6, Myrip, Actc1, AC124993.19, Runx2, AC158560.4, PlekhB1, Rps6KA2, Sept1, Sprr2k, and Flt1.

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