Patent 10907160 was granted and assigned to Ionis Pharmaceuticals on February, 2021 by the United States Patent and Trademark Office.
Provided herein are methods for decreasing LRRK2 mRNA expression. Such methods are useful to ameliorate LRRK2 associated diseases. Such LRRK2 associated diseases include Parkinson's Disease, including non-LRRK2 mediated Parkinson's Disease.