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US Patent 10898506 P-ethoxy nucleic acids for liposomal formulation

Patent 10898506 was granted and assigned to Bio-Path Holdings on January, 2021 by the United States Patent and Trademark Office.

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Is a
Patent
Patent

Patent attributes

Patent Applicant
Bio-Path Holdings
Bio-Path Holdings
Current Assignee
Bio-Path Holdings
Bio-Path Holdings
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10898506
Date of Patent
January 26, 2021
Patent Application Number
16426798
Date Filed
May 30, 2019
Patent Citations
‌
US Patent 10087464 Compositions and methods for delivering nucleic acid to a cell
‌
US Patent 10335428 P-ethoxy nucleic acids for liposomal formulation
Patent Citations Received
‌
US Patent 12012601 Combination therapy with liposomal antisense oligonucleotides
0
Patent Primary Examiner
‌
Tracy Vivlemore
Patent abstract

Provided herein are therapeutic oligonucleotides that comprise at least one p-ethoxy backbone linkage but no more than 80% p-ethoxy backbone linkages. Provided herein are improved delivery systems for therapeutic oligonucleotides comprising a liposome that comprises neutral phospholipids and a p-ethoxy oligonucleotide that is entrapped in the liposome.

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