Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
January 14, 2020
Patent Application Number
15341344
Date Filed
November 2, 2016
Patent Citations
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides for novel methods for regulating and detecting the cytosine methylation status of DNA. The invention is based upon identification of a novel and surprising catalytic activity for the family of TET proteins, namely TET1, TET2, TET3, and CXXC4. The novel activity is related to the enzymes being capable of converting the cytosine nucleotide 5-methylcytosine into 5-hydroxymethylcytosine by hydroxylation.
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