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US Patent 10517894 Restimulation of cryopreserved tumor infiltrating lymphocytes

Patent 10517894 was granted and assigned to Iovance Biotherapeutics, Inc. on December, 2019 by the United States Patent and Trademark Office.

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US Patent 12121541 Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
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US Patent 11975028 Restimulation of cryopreserved tumor infiltrating lymphocytes
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US Patent 11866442 Bifunctional compounds for degrading BTK via ubiquitin proteosome pathway
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Patent abstract

The present disclosure provides methods for re-stimulating TIL populations that lead to improved phenotype and increased metabolic health of the TILs and provides methods of assaying for TIL populations to determine suitability for more efficacious infusion after re-stimulation.

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Ian Frank0
Michael T. Lotze0
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US Patent 11767510 Devices and methods for isolating tumor infiltrating lymphocytes and uses thereof
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US Patent 11618878 Aseptic tissue processing method, kit and device
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US Patent 11618877 Aseptic tissue processing method, kit and device
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US Patent 11530386 Cells expressing recombinant growth factor receptors
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US Patent 11479556 Bifunctional compounds for degrading BTK via ubiquitin proteosome pathway
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