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US Patent 10493106 Method for remolding bone marrow microenvironment

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Patent abstract

The present invention discloses a method for remolding bone marrow microenvironment in a subject having an impaired bone marrow microenvironment, which comprises implanting a composition comprising isolated mesenchymal stromal cells (MSCs) into the bone marrow cavity of the subject. The method of the present invention successfully remolds the bone marrow microenvironment, recovers the normal hematopoiesis of bone marrow, inhibits/delays the pathological process of leukemia and significantly prolongs the survival period. In addition, the method according to the present invention can be used for the treatment of hematologic tumors such as leukemia and aplastic anemia (AA), which is safe and effective but has no side effects.

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US Patent 11557879 Rigid high power and high speed lasing grid structures
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US Patent 11381307 Method and apparatus for alignment of a line-of-sight communications link
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US Patent 10868616 Method and apparatus for alignment of a line-of-sight communications link
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 US Patent 10493106 Method for remolding bone marrow microenvironment

Infobox
Is a
Patent
Patent
Patent jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent number
10493106
Date of patent
December 3, 2019
Patent application number
15869633
Date Filed
January 12, 2018
Patent primary examiner
‌
Sean C. Barron

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