Patent 10473655 was granted and assigned to Chembio Diagnostic Systems, Inc. on November, 2019 by the United States Patent and Trademark Office.
Test devices are provided for determining the presence of a first ligand in a sample. In some embodiments depletion conjugates are used to deplete the ligands different from but related to the first ligands from the sample. In some embodiments, interim binding agents are used to enhance the test signal.