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US Patent 10413569 Microporous zirconium silicate for the treatment of hyperkalemia

Patent 10413569 was granted and assigned to zs pharma on September, 2019 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Patent Applicant
zs pharma
zs pharma
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Current Assignee
zs pharma
zs pharma
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
104135690
Patent Inventor Names
Donald Jeffrey Keyser0
Alvaro F. Guillem0
Date of Patent
September 17, 2019
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Patent Application Number
146922870
Date Filed
April 21, 2015
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Patent Primary Examiner
‌
Kortney L. Klinkel
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Patent abstract

The present invention relates to novel microporous zirconium silicate compositions that are formulated to remove toxins, e.g. potassium ions, from the gastrointestinal tract at an elevated rate without causing undesirable side effects. The preferred formulations are designed avoid increase in pH of urine in patients and/or avoid potential entry of particles into the bloodstream of the patient. Also disclosed is a method for preparing high purity crystals of UZSi-9 exhibiting an enhanced level of potassium exchange capacity. These compositions are particularly useful in the therapeutic treatment of hyperkalemia.

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