Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Akihiro Hashimoto0
Avinash S. Phadke0
Dawei Chen0
Venkat Rao Gadhachanda0
Xiangzhu Wang0
Atul Agarwal0
Godwin Pais0
Jason Allan Wiles0
...
Date of Patent
August 20, 2019
Patent Application Number
15247410
Date Filed
August 25, 2016
Patent Citations Received
...
Patent Primary Examiner
Patent abstract
Compounds, methods of use, and processes for making inhibitors of complement Factor D comprising Formula I, or a pharmaceutically acceptable salt or composition thereof wherein R12 or R13 on the A group is an ether substituent (R32) are provided. The inhibitors described herein target Factor D and inhibit or regulate the complement cascade. The inhibitors of Factor D described herein reduce the excessive activation of complement.
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