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US Patent 10379046 Method and system for multiplexed time-resolved fluorescence detection

Patent 10379046 was granted and assigned to Molecular Devices on August, 2019 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Patent Applicant
Molecular Devices
Molecular Devices
Current Assignee
Molecular Devices
Molecular Devices
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10379046
Patent Inventor Names
Evan F. Cromwell0
Michael Katzlinger0
Vanitha Thulasiraman0
Date of Patent
August 13, 2019
Patent Application Number
14682026
Date Filed
April 8, 2015
Patent Citations Received
‌
US Patent 11971354 Methods and systems for fluorescence detection using infrared dyes
0
Patent Primary Examiner
‌
Bao-Thuy L. Nguyen
Patent abstract

The present invention is directed to a novel method to multiplex long lifetime fluorescent dyes using time-resolved fluorescence (TRF) detection. A combination of spectral and temporal differences in fluorescence emission is used to enhance the ability to separate signals in an assay from multiple dyes. Multiplexed TRF detection apparatuses and systems configured for performing all or part of any of the methods disclosed herein are also provided, particularly apparatuses and systems incorporating cartridge-based multi-mode readers.

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