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US Patent 10363244 Compositions comprising metformin and a glucokinase activator

Patent 10363244 was granted and assigned to vTv Therapeutics on July, 2019 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Patent Applicant
vTv Therapeutics
vTv Therapeutics
Current Assignee
vTv Therapeutics
vTv Therapeutics
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10363244
Patent Inventor Names
Adnan M. M. Mjalli0
Maria Carmen Valcarce Lopez0
Date of Patent
July 30, 2019
Patent Application Number
16058512
Date Filed
August 8, 2018
Patent Citations Received
‌
US Patent 11974989 Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs
0
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US Patent 10952993 Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs
‌
US Patent 11833136 Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs
0
Patent Primary Examiner
‌
Svetlana M Ivanova
Patent abstract

The present invention provides uses of a glucokinase activator in combination with metformin. Uses include treating type 2 diabetes, lowering blood glucose, improving insulin sensitivity, enhancing phosphorylation of glucose, and improving the therapeutic effectiveness of metformin. The invention also provides pharmaceutical compositions that comprise a GK activator and metformin. The invention also provides a salt formed between metformin and a GK activator.

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