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US Patent 10351854 Therapeutic inhibition of lactate dehydrogenase and agents therefor

Patent 10351854 was granted and assigned to Dicerna Pharmaceuticals on July, 2019 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Dicerna Pharmaceuticals

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Current Assignee

Dicerna Pharmaceuticals

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Cheng Lai0

Bob D. Brown0

Henryk T. Dudek0

Date of Patent

July 16, 2019

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Patent Application Number

155180090

Date Filed

October 9, 2015

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Patent Citations Received

US Patent 11053502 Therapeutic inhibition of lactate dehydrogenase and agents therefor

US Patent 11873488 Double-stranded nucleic acid inhibitor molecules modified with Tm-increasing nucleotides

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US Patent 11359203 Therapeutic inhibition of lactate dehydrogenase and agents therefor

US Patent 10738311 Therapeutic inhibition of lactate dehydrogenase and agents therefor

US Patent 11661604 Methods and compositions for inhibiting expression of LDHA

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Patent Primary Examiner

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Patent abstract

This invention relates to compounds, compositions, and methods useful for reducing lactate dehydrogenase target RNA and protein levels via use of dsRNAs, e.g., Dicer substrate siRNA (DsiRNA) agents.

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