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US Patent 10351631 Constant chain modified bispecific, penta- and hexavalent Ig-M antibodies

Patent 10351631 was granted and assigned to IGM Biosciences on July, 2019 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
IGM Biosciences
IGM Biosciences
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Current Assignee
IGM Biosciences
IGM Biosciences
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
103516310
Patent Inventor Names
Bruce Alan Keyt0
Leonard George Presta0
Rency Yoshimura0
Fen Zhang0
Date of Patent
July 16, 2019
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Patent Application Number
149161660
Date Filed
September 4, 2014
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Patent Citations Received
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US Patent 11401337 Modified human IgM constant regions for modulation of complement-dependent cytolysis effector function
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US Patent 10787520 Multimeric bispecific binding molecules specific for CD20 and CD3
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US Patent 10822399 IgA multi-specific binding molecules
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US Patent 10899835 IgM Fc and J-chain mutations that affect IgM serum half-life
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US Patent 11578131 Polynucleotides encoding death domain-containing receptor-5 (DR5) binding molecules
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US Patent 10954302 Anti-PD-L1 antibodies
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US Patent 10975147 Modified J-chain
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US Patent 11639389 Binding molecules with modified J-chain
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...
Patent Primary Examiner
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Julie Wu
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Patent abstract

The present invention concerns binding molecules having a penta- or hexameric ring structure, such as, for example, isolated IgM antibodies with five or six bispecific binding units, and methods and means for making and using the same. The invention further concerns multi-specific binding molecules having a penta- or hexameric ring structure, such as, for example, isolated IgM antibodies with five or six bispecific binding units, and methods and means for making and using the same.

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