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US Patent 10337001 Guide RNA with chemical modifications

Patent 10337001 was granted and assigned to Agilent Technologies on July, 2019 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Agilent Technologies

Current Assignee

Agilent Technologies

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Date of Patent

July 2, 2019

Patent Application Number

15607295

Date Filed

May 26, 2017

Patent Citations Received

US Patent 12084692 Guide scaffolds

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US Patent 11866726 Systems and methods for targeted integration and genome editing and detection thereof using integrated priming sites

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US Patent 11884915 Guide RNAs with chemical modification for prime editing

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US Patent 11492646 Nuclease-mediated genome editing of primary cells

US Patent 11535846 Chemically modified guide RNAS for CRISPR/Cas-mediated gene regulation

US Patent 11634732 Pharmaceutical compositions comprising gene-corrected primary cells

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US Patent 11697827 Systems and methods for gene modification

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US Patent 11306309 Chemically modified guide RNAs for CRISPR/CAS-mediated gene regulation

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Patent Primary Examiner

Channing S Mahatan

Patent abstract

The present invention relates to modified guide RNAs and their use in clustered, regularly interspaced, short palindromic repeats (CRISPR)/CRISPR-associated (Cas) systems.

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