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US Patent 10336744 1AP E3 ligase directed proteolysis targeting chimeric molecules

Patent 10336744 was granted and assigned to GlaxoSmithKline on July, 2019 by the United States Patent and Trademark Office.

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US Patent 12091411 IRAK degraders and uses thereof
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US Patent 12077555 STAT degraders and uses thereof
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US Patent 12006329 Protein degraders and uses thereof
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US Patent 11932624 MDM2 degraders and uses thereof
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US Patent 11932635 CRBN ligands and uses thereof
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Patent abstract

The present invention relates to compounds, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, compositions and medicaments, for example as inhibitors of the activity of RIP2 kinase, including degrading RIP2 kinase, the treatment of diseases and conditions mediated by the RIP2 kinase, in particular for the treatment of inflammatory diseases or conditions.

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US Patent 11779578 IRAK degraders and uses thereof
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Patent Inventor Names
Ian Edward David Smith0
John David Harling0
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US Patent 11746120 Stat degraders and uses thereof
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US Patent 11707457 IRAK degraders and uses thereof
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Official Website
https://pdfpiw.uspto.gov/.piw?Docid=103367440
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US Patent 11685750 Crystalline forms of IRAK degraders
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US Patent 11679109 SMARCA degraders and uses thereof
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US Patent 11623932 Protein degraders and uses thereof
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