Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Sanne Eveline Klompe0
Peter Sean Cameron0
Samuel Henry Sternberg0
Date of Patent
June 25, 2019
0Patent Application Number
162627730
Date Filed
January 30, 2019
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present disclosure provides engineered Class 1 Type I CRISPR-Cas (Cascade) systems that comprise multi-protein effector complexes, nucleoprotein complexes comprising Type I CRISPR-Cas subunit proteins and nucleic acid guides, polynucleotides encoding Type I CRISPR-Cas subunit proteins, and guide polynucleotides. Also, disclosed are methods for making and using the engineered Class 1 Type I CRISPR-Cas systems of the present invention.
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