Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Linda Gillian Durrant0
Rachael Louise Metheringham0
Victoria Anne Brentville0
Date of Patent
March 19, 2019
0Patent Application Number
146149640
Date Filed
February 5, 2015
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Anti-tumor immune responses to modified self-epitopes. The present invention relates to the use of tumor-associated epitopes in medicine and in particular in the treatment of cancer. The epitopes stimulate an immune reaction against the tumor and have a modification selected from deimination of arginine to citrulline, nitration of tyrosine, oxidation of tryptophan and deamination of glutamine or asparagine. The invention also relates to nucleic acids comprising sequences that encode such epitopes for use in the treatment of cancer.
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