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US Patent 10208003 Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds

Patent 10208003 was granted and assigned to Knopp Biosciences on February, 2019 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Patent Applicant
Knopp Biosciences
Knopp Biosciences
Current Assignee
Knopp Biosciences
Knopp Biosciences
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10208003
Date of Patent
February 19, 2019
Patent Application Number
15332599
Date Filed
October 24, 2016
Patent Citations Received
‌
US Patent 11026928 Compositions and methods for treating conditions related to elevated levels of eosinophils and/or basophils
Patent Primary Examiner
‌
Nyeemah A Grazier
Patent abstract

The present invention is related to an improved process for the preparation of amino-substituted 4,5,6,7-tetrahydrobenzothiazole compounds of formula I, such as the compound 2-amino-4,5,6,7-tetrahydro-6-(n-propylamino)benzothiazole. The invention further relates to an improved synthesis of (R)-2-amino-4,5,6,7-tetrahydro-6-(n-propylamino)benzothiazole. The invention also relates to the methods and intermediates associated with the synthetic process.

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