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US Patent 10202375 N-pyridinyl acetamide derivatives as Wnt signalling pathway inhibitors

Patent 10202375 was granted and assigned to Redx Pharma PLC on February, 2019 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Patent Applicant
Redx Pharma PLC
Redx Pharma PLC
Current Assignee
Redx Pharma PLC
Redx Pharma PLC
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10202375
Date of Patent
February 12, 2019
Patent Application Number
15514061
Date Filed
October 8, 2015
Patent Citations Received
‌
US Patent 11643408 N-pyridinyl acetamide derivatives as inhibitors of the WNT signaling pathway
0
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US Patent 10961534 Methods of treating porphyria
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US Patent 11459326 N-pyridinyl acetamide derivatives as Wnt signalling pathway inhibitors
Patent Primary Examiner
‌
Joseph R Kosack
Patent abstract

Disclosed are compounds useful as inhibitors of the Wnt signalling pathway. Specifically, inhibitors of Porcupine (Porcn) are contemplated by the invention. In addition, the invention contemplates processes to prepare the compounds and uses of the compounds. The compounds of the invention may therefore be used in treating conditions mediated by the Wnt signalling pathway, for example, in treating cancer, sarcoma, melanoma, skin cancer, haematological tumors, lymphoma, carcinoma, and leukemia; or enhancing the effectiveness of an anti-cancer treatment.

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