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US Patent 10201527 Benzimidazole derivatives: preparation and pharmaceutical applications

Patent 10201527 was granted and assigned to MEI Pharma on February, 2019 by the United States Patent and Trademark Office.

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Patent abstract

The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to benzimidazole containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with dysregulation of histone deacetylase (HDAC).

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